High-fidelity DNA Polymerases & When to use them
High-fidelity DNA Polymerases & When to use them

Taq polymerase is the tried and true standard when it comes to PCR, but that doesn’t mean it’s the most accurate polymerase for high-sensitivity applications. Instead, alternative enzymes, known as high-fidelity polymerases, offer higher accuracies in the amplicons resulting from PCR thanks to a combination of more stringent base reading and proofreading activities. While you

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Bead Beating & Homogenisation
Bead Beating & Homogenisation

Homogenisation is a popular method of cell disruption through lysis (breaking up) the sample using a homogeniser. This is achieved through mixing at high speeds in tubes with either steel, glass (silica) or zirconium beads added to grind the sample and release subcellular contents of DNA, RNA and proteins. There are lots of homogenisers on

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