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Since the first papers outlining the utility of High Resolution Melting by Carl Wittwer the method has grown in utility and the number of people using the method. High Resolution Melting offers a number of significant advantages compared to alternatives. These include:

  1. Speed
  2. Ease of Use
  3. Cost
  4. Sensitivity
  5. Specificity
Additional Information:
  1. HRM: Advances and Limitations - Paper
  2. HRM: More than just Sequence Variant Screening - Paper
  3. Ultra fast Mutation Scanning and Genotyping - Application Note